Endogenous estrogen is vital for the growth of certain tissues. The role of estrogen in the body is important. Few people realize that levels of estrogen need to be within specific limits. ![]() One of the most important “detoxification” pathways in the human body involves hormones and hormone-like chemicals. These include cytochrome p450 (CYP450) phase 1 detoxification enzymes as well as phase II conjugation enzymes. Research has shown that taking I3C and DIM may increase the expression of certain enzymes. In other words, they can change how your cells make certain proteins. †īoth I3C and DIM have been shown to have the ability to change gene transcription. In the presence of acid in the stomach and some enzymes, this compound can metabolize into another compound known as diindolylmethane or DIM. One chemical that has been isolated from these vegetables is Indole-3-carbinol or I3C. The consumption of broccoli and other cruciferous vegetables has long been associated with supporting normal detoxification processes. When your hormones are balanced and supported, you will feel calm and have healthy energy levels. Seeking Health’s DIM + I3C is an important product to have on hand to support healthy estrogen metabolism. Those with abnormal ovarian tissue growth.Those at risk for uncontrolled cell growth of the breast tissue.Those with a change in menopausal status.Those exposed to toxins and free radicals.The incidence of higher estrogen may be more prevalent in the following individuals: † †ĭIM + I3C can specifically support healthy estrogen metabolism in individuals with high estrogen exposure. Hormones are such a large factor in mental well-being, as they play a part in neurotransmitter balance and feelings of joy. Keeping these balanced helps to support the healthy expression of hormone balancing and detoxification genes. Oxidative stress due to free radicals has a wide impact on all epigenetic controls. PQQ (from Pyrroloquinoline Quinone Disodium Salt) is added to support healthy oxidation of free radicals due to xenoestrogen (chemical estrogen mimickers) exposure and higher estrogen overall. This can put adrenal health, emotional health, and female menses cycles in danger. ![]() However, when estrogen levels get too high from toxin exposure, liver overload, or the use of prescriptions, other important hormones can drop to dangerously low levels. Estrogen, progesterone, testosterone, and other adrenal hormones and sex hormones (androgens) are incredibly important for reproductive health, sexual health, and overall vitality. †Ī healthy balance between steroid hormones is vital. Both DIM and I3C are dietary indoles, which support normal processing of estrogen metabolites. †ĭIM (diindolylmethane) is a byproduct of I3C (indole-3-carbinol), a compound found in broccoli, cabbage and cruciferous vegetables. ![]() The effects of estrogen in high quantities in the body should not be overlooked.ĭo you have estrogen dominance? Are you concerned about supporting a healthy hormone balance? †ĭIM+I3C is a targeted formula that supports healthy estrogen metabolism and a healthy oxidative stress responses associated with xenoestrogen exposure. Toxin exposure typically affects the endocrine system by increasing estrogen production or estrogen activity. In the presence of free radicals, estrogenic activity and estrogen metabolism are influenced. Are you exposed to plastics, conventional meat and dairy, or conventional household products on a regular basis?Īll of these have one thing in common - they contain chemicals that may harm human cells and promote free radicals in the body.
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